The MUSC Healthcare Simulation Center (MUSC HSC) provides an interprofessional, simulation-focused learning environment to enhance the education of healthcare professionals and improve the provision of safe, comprehensive healthcare across the MUSC enterprise. The center occupies approximately 12,000 square feet of space on the second floor of the Colbert Library Building with 13 flexible simulation spaces of varying types, and the center’s inventory of simulators includes 30+ mid to high fidelity manikins and over 100 task trainers to support a broad range of simulation-based educational objectives. Simulation center staff work with simulation session sponsors to assign the most appropriate simulators to meet the educational objectives.